Red Raspberries Research

There is abundant research about the health benefits of Real Red Raspberries. We’ve compiled some of it for you below.

  • Marzban G, Herndl A, Kolarich D, Maghuly F, Mansfeld A, Hemmer W, Katinger H, Laimer M. Identification of four IgE-reactive proteins in raspberry (Rubus ideaeus L.). Mol Nutr Food Res. 2008 Dec;52(12):1497-506

  • Meyer AS, Heinonen M, Frankel EN, Antioxidant interactions of catechin, cyanidin, caffeic acid, quercetin, and ellagic acid on human LDL oxidation, Food Chemistry, Volume 61, Issues 1–2, 1998, Pages 71-75

  • Kähkönen M, Kylli P, Ollilainen V, Salminen JP, Heinonen M. Antioxidantactivity of isolated ellagitannins from red raspberries and cloudberries. J Agric Food Chem. 2012 Feb 8;60(5):1167-74

  • Festa F, Aglitti T, Duranti G, Ricordy R, Perticone P, Cozzi R. Strongantioxidant activity of ellagic acid in mammalian cells in vitro revealed by the comet assay. Anticancer Res. 2001 Nov-Dec;21(6A):3903-8

  • Gauliard B, Grieve D, Wilson R, Crozier A, Jenkins C, Mullen WD, Lean M. The effects of dietary phenolic compounds on cytokine and antioxidant production by A549 cells. J Med Food. 2008 Jun;11(2):382-4

  • Tsuda T. Regulation of adipocyte function by anthocyanins; possibility of preventing the metabolic syndrome. J Agric Food Chem. 2008 Feb 13;56(3):642-6

  • Wang J, Mazza G. Effects of anthocyanins and other phenolic compounds on theproduction of tumor necrosis factor alpha in LPS/IFN-gamma-activated RAW 264.7 macrophages. J Agric Food Chem. 2002 Jul 17;50(15):4183-9

  • Wang J, Mazza G. Inhibitory effects of anthocyanins and other phenoliccompounds on nitric oxide production in LPS/IFN-gamma-activated RAW 264.7 macrophages. J Agric Food Chem. 2002 Feb 13;50(4):850-7

  • Godevac D, Tesević V, Vajs V, Milosavljević S, Stanković M. Antioxidantproperties of raspberry seed extracts on micronucleus distribution in peripheral blood lymphocytes. Food Chem Toxicol. 2009 Nov;47(11):2853-9

  • Vuorela S, Kreander K, Karonen M, Nieminen R, Hämäläinen M, Galkin A, Laitinen L, Salminen JP, Moilanen E, Pihlaja K, Vuorela H, Vuorela P, Heinonen M. Preclinical evaluation of rapeseed, raspberry, and pine bark phenolics for health related effects. J Agric Food Chem. 2005 Jul 27;53(15):5922-31

  • Jean-Gilles D, Li L, Ma H, Yuan T, Chichester CO 3rd, Seeram NP. Anti-inflammatory effects of polyphenolic-enriched red raspberry extract in an antigen-induced arthritis rat model. J Agric Food Chem. 2012 Jun13;60(23):5755-62

  • Sangiovanni E, Vrhovsek U, Rossoni G, Colombo E, Brunelli C, Brembati L, Trivulzio S, Gasperotti M, Mattivi F, Bosisio E, Dell’Agli M. Ellagitannins from Rubus berries for the control of gastric inflammation: in vitro and in vivo studies. PLoS One. 2013 Aug 5;8(8):e71762

  • Seeram NP, Momin RA, Nair MG, Bourquin LD. Cyclooxygenase inhibitory andantioxidant cyanidin glycosides in cherries and berries. Phytomedicine. 2001Sep;8(5):362-9

  • Carmen Ramirez-Tortosa M, García-Alonso J, Luisa Vidal-Guevara M, Quiles JL, Jesús Periago M, Linde J, Dolores Mesa M, Ros G, Abellán P, Gil A. Oxidativestress status in an institutionalised elderly group after the intake of aphenolic-rich dessert. Br J Nutr. 2004 Jun;91(6):943-50

  • Morillas-Ruiz J, Zafrilla P, Almar M, Cuevas MJ, López FJ, Abellán P, Villegas JA, González-Gallego J. The effects of an antioxidant-supplemented beverage on exercise-induced oxidative stress: results from a placebo-controlled double-blind study in cyclists. Eur J Appl Physiol. 2005 Dec;95(5-6):543-9

  • Haleem MA, Barton KL, Borges G, Crozier A, Anderson AS. Increasing antioxidantintake from fruits and vegetables: practical strategies for the Scottish population. J Hum Nutr Diet. 2008 Dec;21(6):539-46

  • Gião MS, Pestana D, Faria A, Guimarães JT, Pintado ME, Calhau C, Azevedo I, Malcata FX. Effects of extracts of selected medicinal plants upon hepaticoxidative stress. J Med Food. 2010 Feb;13(1):131-6

  • Allen CT, Peden-Adams MM, EuDaly J, Keil DE. Subchronic exposure to ellagicacid impairs cytotoxic T-cell function and suppresses humoral immunity in mice. Immunopharmacol Immunotoxicol. 2003 Aug;25(3):409-22

  • Iino T, Tashima K, Umeda M, Ogawa Y, Takeeda M, Takata K, Takeuchi K. Effect of ellagic acid on gastric damage induced in ischemic rat stomachs following ammonia or reperfusion. Life Sci. 2002 Jan 25;70(10):1139-50

  • Ramirez-Tortosa C, Andersen ØM, Cabrita L, Gardner PT, Morrice PC, Wood SG, Duthie SJ, Collins AR, Duthie GG. Anthocyanin-rich extract decreases indices of lipid peroxidation and DNA damage in vitamin E-depleted rats. Free Radic Biol Med. 2001 Nov 1;31(9):1033-7

  • Jakobsdottir G, Blanco N, Xu J, Ahrné S, Molin G, Sterner O, Nyman M. Formation of short-chain Fatty acids, excretion of anthocyanins, and microbial diversity in rats fed blackcurrants, blackberries, and raspberries. J Nutr Metab. 2013;2013:202534

  • Rosillo MA, Sanchez-Hidalgo M, Cárdeno A, de la Lastra CA. Protective effectof ellagic acid, a natural polyphenolic compound, in a murine model of Crohn’s disease. Biochem Pharmacol. 2011 Oct 1;82(7):737-45

  • Duthie SJ, Gardner PT, Morrice PC, Wood SG, Pirie L, Bestwick CC, Milne L, Duthie GG. DNA stability and lipid peroxidation in vitamin E-deficient rats in vivo and colon cells in vitro–modulation by the dietary anthocyanin,cyanidin-3-glycoside. Eur J Nutr. 2005 Jun;44(4):195-203

  • Nasef NA, Mehta S, Murray P, Marlow G, Ferguson LR. Anti-inflammatory activity of fruit fractions in vitro, mediated through toll-like receptor 4 and 2 in the context of inflammatory bowel disease. Nutrients. 2014 Nov 19;6(11):5265-79

  • Figueira ME, Câmara MB, Direito R, Rocha J, Serra AT, Duarte CM, Fernandes A, Freitas M, Fernandes E, Marques MC, Bronze MR, Sepodes B. Chemical characterization of a red raspberry fruit extract and evaluation of its pharmacological effects in experimental models of acute inflammation and collagen-induced arthritis. Food Funct. 2014 Dec;5(12):3241-51

  • Li L, Wang L, Wu Z, Yao L, Wu Y, Huang L, Liu K, Zhou X, Gou D. Anthocyanin-rich fractions from red raspberries attenuate inflammation in both RAW264.7 macrophages and a mouse model of colitis. Sci Rep. 2014 Aug 29;4:6234

  • Chung JG. Inhibitory actions of ellagic acid on growth and arylamineN-acetyltransferase activity in strains of Helicobacter pylori from peptic ulcer patients. Microbios. 1998;93(375):115-27

  • Rauha JP, Remes S, Heinonen M, Hopia A, Kähkönen M, Kujala T, Pihlaja K, Vuorela H, Vuorela P. Antimicrobial effects of Finnish plant extracts containing flavonoids and other phenolic compounds. Int J Food Microbiol. 2000 May 25;56(1):3-12

  • Puupponen-Pimiä R, Nohynek L, Meier C, Kähkönen M, Heinonen M, Hopia A, Oksman-Caldentey KM. Antimicrobial properties of phenolic compounds from berries. J Appl Microbiol. 2001 Apr;90(4):494-507

  • Chatterjee A, Yasmin T, Bagchi D, Stohs SJ. Inhibition of Helicobacter pylori in vitro by various berry extracts, with enhanced susceptibility toclarithromycin. Mol Cell Biochem. 2004 Oct;265(1-2):19-26

  • Lin YT, Vattem D, Labbe RG, Shetty K. Enhancement of antioxidant activity and inhibition of Helicobacter pylori by phenolic phytochemical-enriched alcoholic beverages. Process Biochemistry. 2005 May;40(6):2059-65

  • Puupponen-Pimiä R, Nohynek L, Hartmann-Schmidlin S, Kähkönen M, Heinonen M, Määttä-Riihinen K, Oksman-Caldentey KM. Berry phenolics selectively inhibit the growth of intestinal pathogens. J Appl Microbiol. 2005;98(4):991-1000

  • Nohynek LJ, Alakomi HL, Kähkönen MP, Heinonen M, Helander IM, Oksman-Caldentey KM, Puupponen-Pimiä RH. Berry phenolics: antimicrobial properties and mechanisms of action against severe human pathogens. Nutr Cancer. 2006;54(1):18-32

  • Cavanagh HM, Hipwell M, Wilkinson JM. Antibacterial activity of berry fruits used for culinary purposes. J Med Food. 2003 Spring;6(1):57-61

  • Ryan T, Wilkinson JM, Cavanagh HM. Antibacterial activity of raspberry cordial in vitro. Res Vet Sci. 2001 Dec;71(3):155-9

  • Seeram NP, Nair MG. Inhibition of lipid peroxidation and structure-activity-related studies of the dietary constituents anthocyanins, anthocyanidins, and catechins. J Agric Food Chem. 2002 Sep 11;50(19):5308-12

  • Wolfe KL, Kang X, He X, Dong M, Zhang Q, Liu RH. Cellular antioxidant activity of common fruits. J Agric Food Chem. 2008 Sep 24;56(18):8418-26

  • Borges G, Degeneve A, Mullen W, Crozier A. Identification of flavonoid and phenolic antioxidants in black currants, blueberries, raspberries, red currants, and cranberries. J Agric Food Chem. 2010 Apr 14;58(7):3901-9

  • Pellegrini N, Serafini M, Colombi B, Del Rio D, Salvatore S, Bianchi M, Brighenti F. Total antioxidant capacity of plant foods, beverages and oils consumed in Italy assessed by three different in vitro assays. J Nutr. 2003 Sep;133(9):2812-9

  • Viljanen K, Halmos AL, Sinclair A, Heinonen M. Effect of blackberry and raspberry juice on whey protein emulsion stability. Eur Food Res Technol. 2005 OCT;221(5):602-9

  • Carlsen MH, Halvorsen BL, Holte K, Bøhn SK, Dragland S, Sampson L, Willey C, Senoo H, Umezono Y, Sanada C, Barikmo I, Berhe N, Willett WC, Phillips KM, Jacobs DR Jr, Blomhoff R. The total antioxidant content of more than 3100 foods, beverages, spices, herbs and supplements used worldwide. Nutr J. 2010 Jan 22;9:3

  • Salminen H, Heinonen M. Plant phenolics affect oxidation of tryptophan. J Agric Food Chem. 2008 Aug 27;56(16):7472-81

  • Wada L, Ou B. Antioxidant activity and phenolic content of Oregon caneberries. J Agric Food Chem. 2002 Jun 5;50(12):3495-500

  • Kähkönen MP, Hopia AI, Heinonen M. Berry phenolics and their antioxidant activity. J Agric Food Chem. 2001 Aug;49(8):4076-82

  • Deighton N, Stewart D, Davies HV, Gardner PT, Duthie GG, Mullen W, Crozier A. Soft fruit as sources of dietary antioxidants. Acta Hort. (ISHS) 2002, 585, 459-465.

  • Bermudez-Soto MJ, Tomas-Barberan FA. Evaluation of commercial red fruit juice concentrates as ingredients for antioxidant functional juices. Eur Food Res Technol. 2004 July;219(2):133-41

  • Viljanen K, Kylli P, Kivikari R, Heinonen M. Inhibition of protein and lipid oxidation in liposomes by berry phenolics. J Agric Food Chem. 2004 Dec 1;52(24):7419-24

  • Viljanen K, Kylli P, Hubbermann EM, Schwarz K, Heinonen M. Anthocyanin antioxidant activity and partition behavior in whey protein emulsion. J Agric Food Chem. 2005 Mar 23;53(6):2022-7

  • Pantelidis GE, Vasilakakis M, Manganaris GA, Diamantidis G. Antioxidant capacity, phenol, anthocyanin and ascorbic acid contents in raspberries, blackberries, red currants, gooseberries and Cornelian cherries. Food Chem. 2007;102(3)777–83

  • Garzón GA, Riedl KM, Schwartz SJ. Determination of anthocyanins, totalphenolic content, and antioxidant activity in Andes Berry (Rubus glaucus Benth). J Food Sci. 2009 Apr;74(3):C227-32

  • Henríquez C, López-Alarcón C, Gómez M, Lutz M, Speisky H. Time-dependence of ferric reducing antioxidant power (FRAP) index in Chilean apples and berries. Arch Latinoam Nutr. 2011 Sep;61(3):323-32

  • Komorsky-Lovrić Š, Novak I. Abrasive stripping square-wave voltammetry of blackberry, raspberry, strawberry, pomegranate, and sweet and blue potatoes. J Food Sci. 2011 Aug;76(6):C916-20

  • Chen L, Xin X, Yuan Q, Su D, Liu W. Phytochemical properties and antioxidant capacities of various colored berries. J Sci Food Agric. 2014 Jan 30;94(2):180-8

  • Proteggente AR, Pannala AS, Paganga G, Van Buren L, Wagner E, Wiseman S, Van De Put F, Dacombe C, Rice-Evans CA. The antioxidant activity of regularly consumed fruit and vegetables reflects their phenolic and vitamin C composition. Free Radic Res. 2002 Feb;36(2):217-33

  • Halvorsen BL, Carlsen MH, Phillips KM, Bøhn SK, Holte K, Jacobs DR Jr, Blomhoff R. Content of redox-active compounds (ie, antioxidants) in foods consumed in the United States. Am J Clin Nutr. 2006 Jul;84(1):95-135

  • Amakura Y, Umino Y, Tsuji S, Tonogai Y. Influence of jam processing on the radical scavenging activity and phenolic content in berries. J Agric Food Chem. 2000 Dec;48(12):6292-7

  • Wang SY, Lin HS. Antioxidant activity in fruits and leaves of blackberry, raspberry, and strawberry varies with cultivar and developmental stage. J Agric Food Chem. 2000 Feb;48(2):140-6

  • Wu X, Beecher GR, Holden JM, Haytowitz DB, Gebhardt SE, Prior RL. Lipophilic and hydrophilic antioxidant capacities of common foods in the United States. J Agric Food Chem. 2004 Jun 16;52(12):4026-37

  • Parry J, Su L, Luther M, Zhou K, Yurawecz MP, Whittaker P, Yu L. Fatty acid composition and antioxidant properties of cold-pressed marion berry, boysenberry, red raspberry, and blueberry seed oils. J Agric Food Chem. 2005 Feb 9;53(3):566-73

  • Kalt W, Forney CF, Martin A, Prior RL. Antioxidant capacity, vitamin C, phenolics, and anthocyanins after fresh storage of small fruits. J Agric FoodChem. 1999 Nov;47(11):4638-44

  • Nikitina VS, Shendel GV, Gerchikov AY, Efimenko NB. Flavonoids from raspberry and blackberry leaves and their antioxidant activities. Pharmaceutical Chemistry Journal. 2000 Nov;34(11):596-8.

  • Moyer RA, Hummer KE, Finn CE, Frei B, Wrolstad RE. Anthocyanins, phenolics, and antioxidant capacity in diverse small fruits: vaccinium, rubus, and ribes. J Agric Food Chem. 2002 Jan 30;50(3):519-25

  • Funt RC. Antioxidants in Ohio berries. Acta Hort. (ISHS) 2003.

  • Sariburun E, Sahin S, Demir C, Türkben C, Uylaşer V. Phenolic content and antioxidant activity of raspberry and blackberry cultivars. J Food Sci. 2010May;75(4):C328-35

  • Šaponjac VT, Gironés-Vilaplana A, Djilas S, Mena P, Cetković G, Moreno DA,Canadanović-Brunet J, Vulić J, Stajčić S, Krunić M. Anthocyanin profiles and biological properties of caneberry (Rubus spp.) press residues. J Sci Food Agric. 2014 Sep;94(12):2393-400

  • Sablani SS, Andrews PK, Davies NM, Walters T, Saez H, Syamaladevi RM, Mohekar PR. Effect of thermal treatments on phytochemicals in conventionally and organically grown berries. J Sci Food Agric. 2010 Apr 15;90(5):769-78

  • Verde SC, Trigo MJ, Sousa MB, Ferreira A, Ramos AC, Nunes I, Junqueira C, Melo R, Santos PM, Botelho ML. Effects of gamma radiation on raspberries: safety and quality issues. J Toxicol Environ Health A. 2013;76(4-5):291-303

  • Mullen W, Stewart AJ, Lean ME, Gardner P, Duthie GG, Crozier A. Effect of freezing and storage on the phenolics, ellagitannins, flavonoids, and antioxidant capacity of red raspberries. J Agric Food Chem. 2002 Aug 28;50(18):5197-201

  • Parry J, Su L, Moore J, Cheng Z, Luther M, Rao JN, Wang JY, Yu LL. Chemical compositions, antioxidant capacities, and antiproliferative activities of selected fruit seed flours. J Agric Food Chem. 2006 May 31;54(11):3773-8

  • Chanjiraku K, Wang SY, Wang CY, Siriphanich J. Effect of natural volatile compounds on antioxidant capacity and antioxidant enzymes in raspberries. Postharvest Biology and Technology 2006, 40, (2), 106-115.

  • Remberg SF, Sønsteby A, Aaby K, Heide OM. Influence of postflowering temperature on fruit size and chemical composition of Glen Ample raspberry (Rubusidaeus L.). J Agric Food Chem. 2010 Aug 25;58(16):9120-8

  • Gülçin I, Topal F, Çakmakçı R, Bilsel M, Gören AC, Erdogan U. Pomological features, nutritional quality, polyphenol content analysis, and antioxidant properties of domesticated and 3 wild ecotype forms of raspberries (Rubus idaeus L.). J Food Sci. 2011 May;76(4):C585-93

  • Scalzo J, Mezzetti B, Hall H, McGhie T. Comparing methods for evaluation of raspberry’s quality. Acta Hort. (ISHS) 2004 649, 327-330.

  • Novaković MM, Stevanović SM, Gorjanović SŽ, Jovanovic PM, Tešević VV, Janković MA, Sužnjević DŽ. Changes of hydrogen peroxide and radical-scavenging activity of raspberry during osmotic, convective, and freeze-drying. J Food Sci. 2011 May;76(4):C663-8

  • de Ancos B, González EM, Cano MP. Ellagic acid, vitamin C, and total phenolic contents and radical scavenging capacity affected by freezing and frozen storage in raspberry fruit. J Agric Food Chem. 2000 Oct;48(10):4565-70

  • Tosun M, Ercisli S, Karlidag H, Sengul M. Characterization of red raspberry (Rubus idaeus L.) genotypes for their physicochemical properties. J Food Sci. 2009 Sep;74(7):C575-9

  • Dobson P, Graham J, Stewart D, Brennan R, Hackett CA, McDougall GJ.Over-seasons analysis of quantitative trait loci affecting phenolic content and antioxidant capacity in raspberry. J Agric Food Chem. 2012 May 30;60(21):5360-6

  • Laitinen LA, Tammela PS, Galkin A, Vuorela HJ, Marvola ML, Vuorela PM. Effects of extracts of commonly consumed food supplements and food fractions on the permeability of drugs across Caco-2 cell monolayers. Pharm Res. 2004 Oct;21(10):1904-16

  • Gill CI, McDougall GJ, Glidewell S, Stewart D, Shen Q, Tuohy K, Dobbin A, BoydA, Brown E, Haldar S, Rowland IR. Profiling of phenols in human fecal water after raspberry supplementation. J Agric Food Chem. 2010 Oct 13;58(19):10389-95

  • Cerdá B, Tomás-Barberán FA, Espín JC. Metabolism of antioxidant and chemopreventive ellagitannins from strawberries, raspberries, walnuts, and oak-aged wine in humans: identification of biomarkers and individual variability. J Agric Food Chem. 2005 Jan 26;53(2):227-35

  • González-Barrio R, Borges G, Mullen W, Crozier A. Bioavailability of anthocyanins and ellagitannins following consumption of raspberries by healthy humans and subjects with an ileostomy. J Agric Food Chem. 2010 Apr14;58(7):3933-9

  • González-Barrio R, Edwards CA, Crozier A. Colonic catabolism of ellagitannins, ellagic acid, and raspberry anthocyanins: in vivo and in vitro studies. Drug Metab Dispos. 2011 Sep;39(9):1680-8

  • Cao G, Muccitelli HU, Sánchez-Moreno C, Prior RL. Anthocyanins are absorbed in glycated forms in elderly women: a pharmacokinetic study. Am J Clin Nutr. 2001 May;73(5):920-6

  • Aura AM, Martin-Lopez P, O’Leary KA, Williamson G, Oksman-Caldentey KM, Poutanen K, Santos-Buelga C. In vitro metabolism of anthocyanins by human gut microflora. Eur J Nutr. 2005 Mar;44(3):133-42

  • Talavéra S, Felgines C, Texier O, Besson C, Lamaison JL, Rémésy C. Anthocyanins are efficiently absorbed from the stomach in anesthetized rats. J Nutr. 2003 Dec;133(12):4178-82

  • Woodward G, Kroon P, Cassidy A, Kay C. Anthocyanin stability and recovery: implications for the analysis of clinical and experimental samples. J Agric Food Chem. 2009 Jun 24;57(12):5271-8

  • Daniel EM, Ratnayake S, Kinstle T, Stoner GD. The effects of pH and rat intestinal contents on the liberation of ellagic acid from purified and crude ellagitannins. J Nat Prod. 1991 Jul-Aug;54(4):946-52

  • McDougall GJ, Dobson P, Smith P, Blake A, Stewart D. Assessing potential bioavailability of raspberry anthocyanins using an in vitro digestion system. J Agric Food Chem. 2005 Jul 27;53(15):5896-904

  • Matuschek MC, Hendriks WH, McGhie TK, Reynolds GW. The jejunum is the main site of absorption for anthocyanins in mice. J Nutr Biochem. 2006 Jan;17(1):31-6

  • Chen W, Wang D, Wang LS, Bei D, Wang J, See WA, Mallery SR, Stoner GD, Liu Z. Pharmacokinetics of protocatechuic acid in mouse and its quantification in human plasma using LC-tandem mass spectrometry. J Chromatogr B Analyt Technol Biomed Life Sci. 2012 Nov 1;908:39-44

  • Borges G, Roowi S, Rouanet JM, Duthie GG, Lean ME, Crozier A. The bioavailability of raspberry anthocyanins and ellagitannins in rats. Mol Nutr Food Res. 2007 Jun;51(6):714-25

  • Passamonti S, Vrhovsek U, Mattivi F. The interaction of anthocyanins with bilitranslocase. Biochem Biophys Res Commun. 2002 Aug 23;296(3):631-6

  • Torres-Urrutia C, Guzmán L, Schmeda-Hirschmann G, Moore-Carrasco R, Alarcón M, Astudillo L, Gutierrez M, Carrasco G, Yuri JA, Aranda E, Palomo I. Antiplatelet, anticoagulant, and fibrinolytic activity in vitro of extracts from selected fruits and vegetables. Blood Coagul Fibrinolysis. 2011 Apr;22(3):197-205

  • Yu YM, Wang ZH, Liu CH, Chen CS. Ellagic acid inhibits IL-1beta-induced cell adhesion molecule expression in human umbilical vein endothelial cells. Br J Nutr. 2007 Apr;97(4):692-8

  • Chang WC, Yu YM, Chiang SY, Tseng CY. Ellagic acid suppresses oxidised low-density lipoprotein-induced aortic smooth muscle cell proliferation: studies on the activation of extracellular signal-regulated kinase 1/2 and proliferating cell nuclear antigen expression. Br J Nutr. 2008 Apr;99(4):709-14

  • Labrecque L, Lamy S, Chapus A, Mihoubi S, Durocher Y, Cass B, Bojanowski MW, Gingras D, Béliveau R. Combined inhibition of PDGF and VEGF receptors by ellagic acid, a dietary-derived phenolic compound. Carcinogenesis. 2005 Apr;26(4):821-6

  • Suh JH, Romain C, González-Barrio R, Cristol JP, Teissèdre PL, Crozier A, Rouanet JM. Raspberry juice consumption, oxidative stress and reduction of atherosclerosis risk factors in hypercholesterolemic golden Syrian hamsters. Food Funct. 2011 Jul;2(7):400-5

  • Puupponen-Pimiä R, Seppänen-Laakso T, Kankainen M, Maukonen J, Törrönen R, Kolehmainen M, Leppänen T, Moilanen E, Nohynek L, Aura AM, Poutanen K, Tómas-Barberán FA, Espín JC, Oksman-Caldentey KM. Effects of ellagitannin-rich berries on blood lipids, gut microbiota, and urolithin production in human subjects with symptoms of metabolic syndrome. Mol Nutr Food Res. 2013 Dec;57(12):2258-63

  • Freese R, Vaarala O, Turpeinen AM, Mutanen M. No difference in platelet activation or inflammation markers after diets rich or poor in vegetables, berries and apple in healthy subjects. Eur J Nutr. 2004 Jun;43(3):175-82

  • Lin MC, Yin MC. Preventive effects of ellagic acid against doxorubicin-induced cardio-toxicity in mice. Cardiovasc Toxicol. 2013 Sep;13(3):185-93

  • Chao PC, Hsu CC, Yin MC. Anti-inflammatory and anti-coagulatory activities of caffeic acid and ellagic acid in cardiac tissue of diabetic mice. Nutr Metab
    (Lond). 2009 Aug 14;6:33

  • Mullen W, McGinn J, Lean ME, MacLean MR, Gardner P, Duthie GG, Yokota T, Crozier A. Ellagitannins, flavonoids, and other phenolics in red raspberries and their contribution to antioxidant capacity and vasorelaxation properties. J Agric Food Chem. 2002 Aug 28;50(18):5191-6

  • Yu YM, Chang WC, Wu CH, Chiang SY. Reduction of oxidative stress and apoptosis in hyperlipidemic rabbits by ellagic acid. J Nutr Biochem. 2005 Nov;16(11):675-81

  • Pieszka M, Tombarkiewicz B, Roman A, Migdał W, Niedziółka J. Effect of bioactive substances found in rapeseed, raspberry and strawberry seed oils on blood lipid profile and selected parameters of oxidative status in rats. Environ Toxicol Pharmacol. 2013 Nov;36(3):1055-62

  • Panchal SK, Ward L, Brown L. Ellagic acid attenuates high-carbohydrate, high-fat diet-induced metabolic syndrome in rats. Eur J Nutr. 2013Mar;52(2):559-68

  • Jia H, Liu JW, Ufur H, He GS, Liqian H, Chen P. The antihypertensive effect of ethyl acetate extract from red raspberry fruit in hypertensive rats. Pharmacogn Mag. 2011 Jan;7(25):19-24

  • Rani UP, Kesavan R, Ganugula R, Avaneesh T, Kumar UP, Reddy GB, Dixit M. Ellagic acid inhibits PDGF-BB-induced vascular smooth muscle cell proliferation and prevents atheroma formation in streptozotocin-induced diabetic rats. J Nutr Biochem. 2013 Nov;24(11):1830-9

  • Olgar Y, Ozturk N, Usta C, Puddu PE, Ozdemir S. Ellagic acid reduces L-typeCa2+ current and contractility through modulation of NO-GC-cGMP pathways in rat ventricular myocytes. J Cardiovasc Pharmacol. 2014 Dec;64(6):567-73

  • Ding Y, Zhang B, Zhou K, Chen M, Wang M, Jia Y, Song Y, Li Y, Wen A. Dietary ellagic acid improves oxidant-induced endothelial dysfunction and atherosclerosis: role of Nrf2 activation. Int J Cardiol. 2014 Aug20;175(3):508-14

  • Jayaprakasam B, Vareed SK, Olson LK, Nair MG. Insulin secretion by bioactive anthocyanins and anthocyanidins present in fruits. J Agric Food Chem. 2005 Jan 12;53(1):28-31

  • Tsuda T. Regulation of adipocyte function by anthocyanins; possibility of preventing the metabolic syndrome. J Agric Food Chem. 2008 Feb 13;56(3):642-6

  • Mathew AJ, Raj NN, Sugappriya M, Priyadarshini SM. Modeling of ATP-sensitive inward rectifier potassium channel 11 and inhibition mechanism of the natural ligand, ellagic acid, using molecular docking. Adv Exp Med Biol. 2010;680:489-95

  • McDougall GJ, Shpiro F, Dobson P, Smith P, Blake A, Stewart D. Different polyphenolic components of soft fruits inhibit alpha-amylase andalpha-glucosidase. J Agric Food Chem. 2005 Apr 6;53(7):2760-6

  • Grussu D, Stewart D, McDougall GJ. Berry polyphenols inhibit α-amylase in vitro: identifying active components in rowanberry and raspberry. J Agric Food Chem. 2011 Mar 23;59(6):2324-31

  • Clegg ME, Pratt M, Meade CM, Henry CJ. The addition of raspberries and blueberries to a starch-based food does not alter the glycaemic response. Br J Nutr. 2011 Aug;106(3):335-8

  • Törrönen R, Kolehmainen M, Sarkkinen E, Poutanen K, Mykkänen H, Niskanen L. Berries reduce postprandial insulin responses to wheat and rye breads in healthy women. J Nutr. 2013 Apr;143(4):430-6

  • Chao PC, Hsu CC, Yin MC. Anti-inflammatory and anti-coagulatory activities of caffeic acid and ellagic acid in cardiac tissue of diabetic mice. Nutr Metab(Lond). 2009 Aug 14;6:33

  • Chao CY, Mong MC, Chan KC, Yin MC. Anti-glycative and anti-inflammatory effects of caffeic acid and ellagic acid in kidney of diabetic mice. Mol Nutr Food Res. 2010 Mar;54(3):388-95

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